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| reproductive immunology ： ウィキペディア英語版 |
reproductive immunology
Reproductive immunology refers to a field of medicine that studies interactions (or the absence of them) between the immune system and components related to the reproductive system, such as maternal immune tolerance towards the fetus, or immunological interactions across the blood-testis barrier. The concept has been used by fertility clinics to explain the fertility problems, recurrent miscarriages and pregnancy complications observed when this state of immunological tolerance is not successfully achieved. Immunological therapy is the new up and coming method for treating many cases of previously "unexplained infertility" or recurrent miscarriage.〔Pearson, H. Immunity’s Pregnant Pause. Nature Publishing Group.2002; 420: 265-266.〕
==Between mother and fetus==
(詳細はorgan transplant, it is not normally rejected, suggests that the immunological system of the mother plays an important role in pregnancy. The placenta also plays an important part in protecting the embryo for the immune attack from the mother's system. Studies also propose that proteins in semen may help woman’s immune system prepare for conception and pregnancy. For example, there is substantial evidence for exposure to partner's semen as prevention for pre-eclampsia, largely due to the absorption of several immune modulating factors present in seminal fluid, such as transforming growth factor beta (TGFβ).〔(【引用サイトリンク】 title=Research Goals --> Role of seminal fluid signalling in the female reproductive tract )〕
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
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